What is Osteoarthritis?

Osteoarthritis (OA) is the most common form of arthritis, affecting millions of people worldwide. Often called “wear and tear” arthritis, it occurs when the protective cartilage that cushions the ends of bones gradually breaks down over time. As cartilage deteriorates, bones may begin to rub against each other, causing pain, stiffness, and reduced mobility.

Unlike inflammatory forms of arthritis such as rheumatoid arthritis, osteoarthritis is primarily a degenerative condition. However, inflammation can develop as the joint damage progresses. OA most commonly affects weight-bearing joints such as the knees and hips, as well as the hands, spine, and feet.

While the joint damage caused by osteoarthritis cannot be reversed, symptoms can often be managed effectively. Staying active, maintaining a healthy weight, and working with your healthcare provider on a treatment plan can help slow disease progression, reduce pain, and improve joint function.

Who is at Risk for Osteoarthritis?

Several factors can increase the likelihood of developing osteoarthritis. Some are related to aging and genetics, while others involve lifestyle and joint health:

  • Age: The risk of osteoarthritis increases with age as cartilage naturally wears down over time
  • Sex: Women are more likely to develop OA, particularly after menopause
  • Excess weight: Carrying extra body weight places additional stress on weight-bearing joints such as the knees and hips, and fat tissue produces proteins that can cause inflammation in and around joints
  • Joint injuries: Previous injuries from sports, accidents, or repetitive strain can increase the risk of OA in that joint, even years later
  • Genetics: A family history of osteoarthritis may increase your likelihood of developing the condition
  • Bone deformities: Some people are born with malformed joints or defective cartilage that increases OA risk
  • Occupation: Jobs that involve repetitive stress on a particular joint, such as kneeling, squatting, or heavy lifting, may contribute to OA over time
  • Other conditions: Metabolic diseases such as diabetes and hemochromatosis can increase risk
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Symptoms of Osteoarthritis

Osteoarthritis symptoms typically develop gradually and worsen over time. The severity of symptoms varies from person to person, and some people experience mild discomfort while others have pain that significantly affects daily activities.

Common symptoms of OA include:

  • Pain in affected joints during or after movement
  • Stiffness, particularly in the morning or after periods of inactivity, usually lasting less than 30 minutes
  • Tenderness when light pressure is applied to the joint
  • Loss of flexibility and reduced range of motion
  • A grating or crackling sensation (crepitus) when moving the joint
  • Swelling around the joint caused by soft tissue inflammation
  • Bone spurs, which are hard lumps that may form around the affected joint
Joints most commonly affected by osteoarthritis

How is Osteoarthritis Diagnosed?

Diagnosing osteoarthritis involves a combination of medical history, physical examination, and diagnostic testing. Your provider will work to confirm OA and rule out other conditions that can cause similar symptoms.

Medical History and Physical Exam

Your provider will ask about your symptoms, when they started, which joints are affected, and what makes the pain better or worse. During the physical exam, they will check for tenderness, swelling, redness, and range of motion in your joints. They may also assess joint stability and listen for crepitus during movement.

Imaging

  • X-rays can reveal cartilage loss by showing a narrowing of the space between bones in a joint, as well as bone spurs and other changes characteristic of OA. However, X-ray findings do not always correlate with symptom severity.
  • MRI may be used in some cases to provide more detailed images of cartilage, bone, and soft tissues, particularly when the diagnosis is unclear or surgery is being considered.

Lab Tests

There is no blood test that diagnoses osteoarthritis, but your provider may order tests to rule out other conditions such as rheumatoid arthritis or gout. Joint fluid analysis, in which a sample of fluid is withdrawn from the affected joint, can help distinguish OA from inflammatory or infectious forms of arthritis.

Treatment for Osteoarthritis

There is no cure for osteoarthritis, but a range of treatments can help manage pain, improve joint function, and maintain quality of life. Your provider will recommend a treatment approach based on the severity of your symptoms and which joints are affected.

Lifestyle Modifications
Medications
Surgery

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